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NameDescriptionMolecular FunctionCellular ComponentBiological Process
SIPA1L3 Unclassified GTPase activator activity,
protein binding
intracellular regulation of small GTPase mediated signal transduction
SIP (RNA-binding motif protein 14) RNA binding protein ligand-dependent nuclear receptor transcription coactivator activity,
RNA binding,
RNA polymerase II transcription mediator activity,
nucleotide binding,
protein binding, bridging
transcription factor complex,
ribonucleoprotein complex,
mediator complex
response to hormone stimulus,
DNA replication,
DNA recombination,
transcription,
DNA repair,
histone deacetylation,
estrogen receptor signaling pathway,
glucocorticoid receptor signaling pathway,
positive regulation of transcription from RNA polymerase II promoter
SIPA1 Unclassified Rap GTPase activator activity perinuclear region of cytoplasm,
nucleus,
membrane,
endomembrane system
intracellular signaling pathway,
regulation of small GTPase mediated signal transduction,
cell proliferation,
negative regulation of cell growth,
signal transduction,
cytoskeleton organization,
negative regulation of cell adhesion,
negative regulation of cell cycle
SIPA1L1 Unclassified GTPase activator activity,
protein binding
cell junction,
cytoplasm,
synaptosome,
dendritic spine,
postsynaptic membrane,
postsynaptic density
activation of Rap GTPase activity,
actin cytoskeleton reorganization,
regulation of dendritic spine morphogenesis
SIPA1L2 Signal-induced proliferation-associated 1-like protein 2. GTPase activator activity,
protein binding
intracellular regulation of small GTPase mediated signal transduction
SIP1 protein binding cytosol,
Cajal body,
spliceosomal complex
spliceosome assembly,
spliceosomal snRNP assembly

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